Who we are:
We investigate the biology of biomolecular systems using theoretical and
computational methods in atomic scales.
Aims of the Lab:
We have an inderdisciplinary program at the interface of biology, physics,
chemistry, and computational sciences to tackle challenging problems
related to human diseases. Our research lab is located at the Jupiter
Research Triangle (Florida Atlantic University, Scripps Florida, and Max
Planck Florida). We develop novel computational methods and models to
study the properties of RNA, DNA, and protein molecules, and study how they
interact with small molecules and ligands.
The lab actively collaborates with several experimental research groups
to improve the quality of computational models describing RNA molecules
such as Prof. Matthew D. Disney (Scripps FL), Prof. Matthew A. Fountain
(SUNY Fredonia), Prof. Ryszard and Ela Kierzek (Polish Academy of
Sciences). Other collaborators include Prof. David J. Wales (University
of Cambridge), Prof. Serdal Kirmizialtin (NYU-Abu Dhabi), and Prof.
Frederick D. Lewis (Northwestern).
Specific programs of current research include the study of RNA repeat
expansions causing genetic diseases (Huntington's Disease, Myotonic
Dystrophy, Fragile X-Syndrome), drug development for RNA-associated
diseases, method development in the studies of challenging RNA systems,
nucleosome and transcription factors, the study of microRNA
molecules, and properties of exotic nucleic acid systems.
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